Large language models get a polished front end that can run fully offline: Open WebUI is the self-hosted front end of choice. It talks to local model runners, primarily Ollama, and to any OpenAI-compatible API, so LM Studio, vLLM, Groq, Mistral, OpenRouter, and cloud providers all plug into the same chat interface and can be mixed per conversation. RAG is built in: upload files to knowledge bases or reference them in chat with the # command, backed by a choice of nine vector databases (ChromaDB and PGVector officially maintained) and multiple extraction engines including Tika and Docling, with hybrid BM25-plus-vector search and cross-encoder reranking. Web search results from providers like SearXNG, Brave, and Tavily inject directly into conversations. Extensibility comes from Python tools and functions that run inside the chat, a Pipelines plugin framework, and native MCP support. Multi-user features include RBAC, SSO, and group permissions, and the instance itself exposes an OpenAI-compatible API your own apps can call.

Drag nodes onto a canvas and ship an LLM app: Flowise is an open-source visual builder for AI agents and LLM applications, written in Node.js on LangChain.js and licensed Apache-2.0. You assemble flows by dragging nodes onto a canvas: models, prompts, memory, vector stores, retrievers, and tools, then wire them together and test in the built-in chat panel. Three builder types cover increasing complexity: Assistant for simple RAG chat over uploaded files, Chatflow for single-agent systems with techniques like rerankers and Graph RAG, and Agentflow for multi-agent orchestration with branching, looping, shared flow state, and human-in-the-loop checkpoints. Over 100 integrations connect data sources, vector databases, and both proprietary and open-source models, plus MCP client and server nodes for standard tool interop. Finished flows are exposed as REST APIs, embedded chat widgets, or via JS and Python SDKs - each flow gets an endpoint the moment it is saved, removing the deployment gap between a working prototype and something your application can call. Execution logs, visual step debugging, and external log streaming trace behavior, while input moderation and rate limiting act as guardrails; RBAC, SSO, and workspaces cover team deployments. Self-hosting keeps prompts, encrypted credentials, and conversation data on your own instance, which matters when flows handle internal documents or customer data - and wiring a model, prompt, memory, and vector store on the canvas replaces the boilerplate a hand-coded LangChain project would need.

A self-hosted "second brain": Khoj indexes your own files and answers questions from them, parsing Markdown (whole Obsidian vaults included), org-mode, PDF, Word, plain text, Notion pages, GitHub repositories, and images described by a vision model, then embedding everything with sentence-transformers into a vector index for semantic search and RAG with cited sources. Any LLM backend works: local models like Llama, Qwen, or Mistral via Ollama, or cloud models like GPT, Claude, and Gemini. You can build custom agents, each with its own persona, scoped knowledge base, chat model, and tools such as web search and code execution. Scheduled automations run recurring research and deliver newsletters or notifications to your inbox, and research mode performs multi-hop web searches with inline citations. Access it from a browser, the Obsidian plugin, Emacs, desktop, or WhatsApp - all clients connect to the same self-hosted instance, making Khoj one of the few AI assistants Emacs users can point at decades of org files. Semantic search means recall works without exact keywords: "that paper about forecasting with transformers" surfaces the right PDF even when you cannot remember its title. Switching LLM backends never requires re-indexing your documents, and with a local model via Ollama, even inference stays on hardware you control - journals, research, and private notes are never sent anywhere. Python/FastAPI stack, AGPL-licensed, with PostgreSQL storage.

Chat with your own documents: AnythingLLM, from Mintplex Labs, wraps retrieval-augmented generation (RAG) in an open-source application anyone can run. You organize content into workspaces, each an isolated namespace with its own documents, vector embeddings, chat history, and settings, so one instance can hold several separate knowledge bases. Upload PDFs, DOCX, TXT, and other formats, or scrape web pages; the built-in collector parses and chunks them into a vector database (LanceDB by default, with Pinecone, Chroma, Qdrant, and others supported). Answers cite their source documents. It works with both cloud LLMs (OpenAI, Anthropic, Gemini) and local ones via Ollama or LM Studio, and the embedding model is separately configurable. Beyond RAG chat, it includes AI agents that can browse the web and run tools, an embeddable chat widget for your website, a developer API, and multi-user mode with admin, manager, and default roles plus per-workspace access control. Context assembly is smarter than naive RAG: pinned documents, attached files, vector search hits, and recent chat history are combined under a token budget so the model's context window is filled efficiently, and each workspace supports multiple independent conversation threads against the same knowledge base. Because the embedding model, vector store, and chat LLM are all independently swappable, you can move between providers without re-ingesting a single document. The stack is Node.js with a React frontend, MIT-licensed.

Retrieval-augmented chatbots on your own knowledge base - that is the whole mission of Dialoqbase, an open-source bot-building platform. Feed it content through a broad set of data loaders - web pages and full crawls, sitemaps, PDFs, DOCX, CSV, plain text, GitHub repositories, YouTube videos, and MP3/MP4 audio - and it handles the whole RAG pipeline in one self-contained app: chunking, embedding, vector storage, and LLM querying. The distinguishing architecture choice is PostgreSQL with pgvector for embedding storage and similarity search, which removes the separate vector-database dependency, and Redis-backed Bull queues for ingesting large documents without blocking the API. Model choice is wide open: OpenAI, Anthropic Claude, Google Gemini, Cohere, Fireworks, Hugging Face, local models via Ollama, and any OpenAI-compatible endpoint, with an equally broad list of embedding providers. Finished bots embed on any website with customizable styling or deploy to Telegram, Discord, and WhatsApp, and an API creates and manages bots programmatically. Multi-user support adds registration limits and per-user bot quotas. MIT-licensed and free for commercial use.